New discovery enhances cell entry for complex cancer drugs

Scientists 'hack' cell entry to supercharge cancer drugs

Scientists could reshape cancer treatment by helping powerful drugs work better in the body by exploiting a surface protein called CD36 that helps pull substances into cells. This dramatically improves the uptake of a promising class of cancer-fighting drugs called PROTACs. The new drug design deliveries up to 22 times more of he drug inside cancer cells, and tumor suppression in mice.

New discovery enhances cell entry for complex cancer drugs

A new discovery could pave the way for more effective cancer treatment by helping certain drugs work better inside the body.

A Cell Trick That Makes Cancer Drugs 23x Stronger

Scientists have found a surprising new way to make certain cancer drugs work dramatically better – by helping them get inside cells more easily. These drugs, called PROTACs, are often too large to enter cells on their own. But researchers discovered that by guiding them through a natural cell protein called CD36, they could deliver [...]

A team of medical researchers from Tel Aviv University (TAU) managed to identify a mechanism that, when reversed, allows the immune system to fight immunotherapy-resistant tumors. The study, led by Carmit Levy, Yaron Carmi and PhD student Avishai Maliah, was published in the prestigious journal Nature Communications. According to Carmit Levy, the finding arose in his laboratory that specializes in cancer research and the effects of ultraviolet r…

'They kill diseased cells 400 times faster!'

Scientists have identified a new methodology to make certain anticancer drugs significantly optimize their functioning by helping them enter cells more easily. The new strategy can enhance up to 23 times the effectiveness of treatments.