Porphyromonas gingivalis bacteremia increases the permeability of the blood-brain barrier via the Mfsd2a/Caveolin-1 mediated transcytosis pathway

Porphyromonas gingivalis bacteremia increases the permeability of the blood-brain barrier via the Mfsd2a/Caveolin-1 mediated transcytosis pathway

Bacteremia induced by periodontal infection is an important factor for periodontitis to threaten general health. P. gingivalis DNA/virulence factors have been found in the brain tissues from patients with Alzheimer’s disease (AD). The blood-brain barrier (BBB) is essential for keeping toxic substances from entering brain tissues. However, the effect of P. gingivalis bacteremia on BBB permeability and its underlying mechanism remains unclear. In …

Arizona State University Alzheimer's study focuses on virus' possible link to disease

Ben Readhead and Diego Mastroeni, associate research professors at the ASU-Banner Neurodegenerative Disease Research Center discuss how human cytomegalovirus (HCMV) can cause a gut infection that potentially could affect the brain.

PacBio Chosen as Tech Partner for Global Alzheimer’s Disease Research Project

The project, the North African Dementia Registry, will unite multiple entities for the purpose of developing a comprehensive dataset to advance the research community’s understanding of Alzheimer’s disease and other dementias in diverse populations.

Alzheimer’s disease caregiver support initiative offers support for local caregivers, families

ADCSI looks forward to hosting May education trainings in Clinton County.Virtual sessions each Tuesday in May (May 6, May 13, May 20 and May 27) beginning at noon.

How others can help the caregiver

Want to help a caregiver? First, recognize that it’s very difficult for someone to ask for help.

Immune Dysfunction and Inflammation Play Significant Role in Alzheimer’s Disease

Temple University, Philadelphia - Brain tissue analysis of an animal model reveals the potential role of immune system dysfunction in the onset and progression of Alzheimer’s Disease (AD).