US EditionAntibiotic conjugates: Using molecular Trojan Horses to overcome drug resistance - AMR Insights
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Antibiotic conjugates: Using molecular Trojan Horses to overcome drug resistance - AMR Insights
Antimicrobial resistance (AMR) is a global health crisis due to multi-drug-resistant bacteria. The ‘Trojan Horse’ strategy involves conjugating antibiotics with bioactive components to enhance their effectiveness against recalcitrant pathogens. This review discusses research on antibiotic conjugates with monoclonal antibodies, antimicrobial peptides, and iron-chelating siderophores. Challenges in clinical translation and future research directio…
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