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Accurate RNA 3D structure prediction using a language model-based deep learning approach

Summary by Nature
Accurate prediction of RNA three-dimensional (3D) structures remains an unsolved challenge. Determining RNA 3D structures is crucial for understanding their functions and informing RNA-targeting drug development and synthetic biology design. The structural flexibility of RNA, which leads to the scarcity of experimentally determined data, complicates computational prediction efforts. Here we present RhoFold+, an RNA language model-based deep lear…

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Accurate RNA 3D structure prediction using a language model-based deep learning approach

Accurate prediction of RNA three-dimensional (3D) structures remains an unsolved challenge. Determining RNA 3D structures is crucial for understanding their functions and informing RNA-targeting drug development and synthetic biology design. The structural flexibility of RNA, which leads to the scarcity of experimentally determined data, complicates computational prediction efforts. Here we present RhoFold+, an RNA language model-based deep lear…

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Aqemia Secures $7.4M To Expand RNA-Targeting Programs With Physics-Based Generative AI

Aqemia has announced a $7.4 million grant from the France 2030 investment plan to accelerate its work in RNA-targeted drug discovery. The funding will support the expansion of its generative AI platform—originally developed for protein targets—to address the complexity of RNA structures and RNA-modifying enzymes. Aqemia’s approach combines physics-based algorithms and statistical mechanics to drive drug design without depending on experimental d…

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Plato. Vertical Search. Ai. | PlatoAiStream. Data Intelligence. Vertical Search. Ai. broke the news in on Wednesday, April 2, 2025.
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