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How Senolytic Compounds Fight Both Aging and Alzheimer's Disease

Summary by AMPLYFI
A recent study published in the journal Aging in March 2025 has identified a potential new therapeutic mechanism for Alzheimer’s disease treatment. The research reveals that senolytic compounds – drugs designed to clear senescent cells – may also selectively inhibit cholinesterase enzymes associated with Alzheimer’s pathology. This study, conducted by researchers at Dalhousie University, demonstrates that several senolytic agents – including das…

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The Hamilton SpectatorThe Hamilton Spectator
+2 Reposted by 2 other sources
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Axsome Therapeutics Presents Positive Pivotal Phase 3 Results of the ACCORD-2 Trial of AXS-05 in Alzheimer’s Disease Agitation and the SYMPHONY Trial of AXS-12 in Narcolepsy at the 2025 American Academy of Neurology (AAN) Annual Meeting

Late-breaking oral presentation of results from the positive pivotal ACCORD-2 Phase 3 trial of AXS-05 in Alzheimer’s disease agitation

·Hamilton, Canada
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AMPLYFIAMPLYFI

How Senolytic Compounds Fight Both Aging and Alzheimer's Disease

A recent study published in the journal Aging in March 2025 has identified a potential new therapeutic mechanism for Alzheimer’s disease treatment. The research reveals that senolytic compounds – drugs designed to clear senescent cells – may also selectively inhibit cholinesterase enzymes associated with Alzheimer’s pathology. This study, conducted by researchers at Dalhousie University, demonstrates that several senolytic agents – including das…

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The Hamilton Spectator broke the news in Hamilton, Canada on Friday, April 4, 2025.
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