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Bristol Myers Squibb Schizophrenia Drug Fails Pivotal Test as an Add-On to Antipsychotics

  • Bristol Myers Squibb's drug Cobenfy failed a pivotal Phase 3 trial on Tuesday.
  • The test aimed to support expanding Cobenfy's use as an adjunctive schizophrenia treatment.
  • Researchers evaluated Cobenfy alongside standard antipsychotics in adults with uncontrolled symptoms.
  • Cobenfy showed a numerical improvement but did not achieve statistical significance versus placebo at week six.
  • This outcome impacts commercial prospects and prompted analysts to reduce revenue projections for the drug.
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The Huntsville Item broke the news in on Tuesday, April 22, 2025.
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