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New genetic clues uncovered in epilepsy drug resistance

  • A new study in *eBioMedicine* revealed common genetic variants linked to drug resistance in epilepsy.
  • Many individuals with epilepsy do not respond to antiseizure medications, leading to drug resistance.
  • Researchers at UCL and UTHealth Houston examined genomes from 6,826 people, comparing drug-resistant cases to controlled ones.
  • Professor Sisodiya stated the findings offer insights and genetic variants could be early biomarkers.
  • Identifying genetic signatures early may predict drug resistance and improve personalized treatment for polygenic epilepsy.
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340breport.com broke the news in on Tuesday, April 15, 2025.
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