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Drug-delivering aptamers target leukemia stem cells for a one-two knockout punch

Summary by Phys.org
Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers at the University of Illinois Urbana-Champaign report.

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Drug-delivering aptamers target leukemia stem cells for one-two knockout punch

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers at the University of Illinois Urbana-Champaign report. The aptamers -- short single-strand snippets of DNA that can target molecules like larger antibodies do -- not only deliver cancer-fighting drugs, but also are themselves toxic to the cancer stem cells, the researchers said.

·United States
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Drug-delivering aptamers target leukemia stem cells for a one-two knockout punch

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers at the University of Illinois Urbana-Champaign report.

·United Kingdom
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Aptamers: Targeting Leukemia Stem Cells for a Dual Knockout Approach

A groundbreaking study conducted by researchers at the University of Illinois Urbana-Champaign presents a novel approach to combat leukemia through targeted drug delivery using DNA aptamers. These short strands of DNA, akin to naturally occurring antibodies, possess the remarkable ability to specifically recognize and bind to cancerous cells. The research team’s approach not only focuses on delivering potent anticancer drugs directly to leukemia…

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Phys.org broke the news in United Kingdom on Thursday, April 3, 2025.
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