US EditionEffect of microcrystalline cellulose (MCC) grade on the properties of twin-screw melt granulated formulations of ascorbic acid - ECP 2025 Poster - Pharma Excipients
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Effect of microcrystalline cellulose (MCC) grade on the properties of twin-screw melt granulated formulations of ascorbic acid - ECP 2025 Poster - Pharma Excipients
This poster was presented at the ECP 2025 in Porto Introduction The agglomeration of fine powders during the twin-screw melt granulation (TSMG) occurs due to the softening or melting of thermal binders, consolidation by kneading (applied mechanical forces) and cooling to room temperature along with formation of solid bridges of solidified binder with relatively low temperature melting peak (Mp). Continuous melt granulation is gaining popularity…
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