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Esketamine Combo Bests SSRIs for Resistant Depression in Head-to-Head Trial

Summary by Medscape
Treatment with esketamine combined with an SNRI is linked to fewer adverse outcomes than treatment with an SSRI alone. Medscape Medical News

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Esketamine Combo Bests SSRIs for TRD in Head-to-Head Trial

Esketamine combined with a serotonin-norepinephrine reuptake inhibitor (SNRI) for treatment-resistant depression (TRD) was linked to significantly lower rates of several adverse outcomes than esketamine plus a selective serotonin reuptake inhibitor (SSRI), new research showed. Prior research has suggested that esketamine combined with either antidepressant is effective for TRD. But whether an add-on SNRI would yield […] The post Esketamine Combo…

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MedscapeMedscape

Esketamine Combo Bests SSRIs for Resistant Depression in Head-to-Head Trial

Treatment with esketamine combined with an SNRI is linked to fewer adverse outcomes than treatment with an SSRI alone. Medscape Medical News

·United States
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Medscape broke the news in United States on Friday, April 4, 2025.
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