Genetic susceptibility to schizophrenia through neuroinflammatory pathways associated with retinal thinness

Genetic susceptibility to schizophrenia through neuroinflammatory pathways associated with retinal thinness

Schizophrenia is associated with structural and functional changes in the central nervous system, including the most distal part of it, the retina. However, the question of whether retinal atrophy is present before individuals develop schizophrenia or is a secondary consequence of the disorder remains unanswered. Here we address this question by examining the association between polygenic risk scores for schizophrenia and retinal morphologies in…

Retinal thinning linked to genetic risk factors for schizophrenia

The retina is part of the central nervous system, and therefore a direct extension of the brain. This is why changes in the brain could potentially also be detected in our eyes. An international team of researchers led by the University of Zurich and the University Hospital of Psychiatry Zurich has now tackled this very question.

Schizophrenia is a serious mental illness that affects the way a person thinks, feels and behaves. People with schizophrenia may seem as if they had lost contact with reality, which can be distressing for them, their family and friends, according to the portal of the National Institute of Mental Health of the United States. In this case the pathology could be applied to a group of people, or a sector of the economy in particular. On the morning …

Eye scans may help detect risk for schizophrenia

A new study led by scientists from the University of Zurich and the University Hospital of Psychiatry Zurich has found a possible link between a person’s genetic risk for schizophrenia and changes in the retina—the light-sensitive tissue at the back of the eye. Because the retina is part of the central nervous system, it shares […] The post Eye scans may help detect risk for schizophrenia appeared first on Knowridge Science Report.

Cortex Thinning Links to Schizophrenia Deficit Symptoms

In a groundbreaking new study published in BMC Psychiatry, researchers have unveiled compelling evidence linking the thinning of specific brain regions—the temporal and insular cortices—to the most debilitating symptoms of schizophrenia, a chronic mental health disorder that affects millions worldwide. This pioneering research, conducted within a uniquely defined cohort of Chinese chronic schizophrenia patients categorized with deficit syndrome …

A new study led by the University of Zurich shows that evidence of an increased risk of schizophrenia can already be found in the retina. This could contribute to better early detection in the future.