Largest single-cell map of the aging brain reveals vulnerable cell types and regions

Largest single-cell map of the aging brain reveals vulnerable cell types and regions

A new study published in Nature offers the most detailed map to date of how individual cell types in the brain change with age. Scientists analyzed over 1.2 million brain cells from young and aged mice and found that many specific cells undergo significant gene expression changes as animals grow older. These changes were not spread evenly throughout the brain. Instead, they clustered in a particular region: the hypothalamus, a part of the brain …

Geographical variations impact brain aging

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Geographic diversity affects brain age

Researchers found that geographic and socioeconomic differences in inequality, pollution levels, gender bias, and disease burden can accelerate brain aging.