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Herpes virus and head injuries linked to Alzheimer’s, mini-brain study finds

  • A study of human brain organoids suggested a complex relationship between herpes simplex virus 1 infection and tau, suggesting that tau phosphorylation may act as an innate immune response in Alzheimer's disease.
  • Topline results from a HEALEY platform trial showed that fosigotifator did not meet its primary endpoint in amyotrophic lateral sclerosis .
  • Another HEALEY trial testing the eIF2B agonist DNL343 also failed to slow disease progression in ALS, Denali Therapeutics said.
  • Linked Medicaid and Medicare records suggested an elevated prevalence of dementia diagnoses in people with autism spectrum disorder.
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