US EditionEarly detection of Alzheimer's disease through blood biomarker
- A new study, published April 16, 2025, explored dementia biomarkers and factors influencing them.
- Researchers aimed to determine how elements like age, sex, hormones, and genetics affect blood biomarkers related to dementia risk.
- The study involved over 1,000 participants and measured three biomarkers over 17 years, comparing those with and without dementia.
- Hannah Stocker stated that blood tests detecting biomarkers for dementia are becoming important tools for understanding these conditions.
- The study indicated that older age links to higher biomarker levels, and sex and genetics also affect these dementia-related biomarkers.
17 Articles
17 Articles
Neurofilament-light chain quantification by Simoa and Ella in plasma from patients with dementia: a comparative study
Neurofilament light chains (NfL) are neuron-specific cytoskeletal proteins whose plasmatic concentrations have been explored as a clinically useful marker in several types of dementia. Plasma concentrations of NfL are extremely low, and just two assays are commercially available for their study: one based on the SiMoA technology and one based on Ella. We thus studied plasma levels of NfL with both platforms to check the correlation between them …
Taiwan doctors help develop 90% accurate Alzheimer's blood test - Focus Taiwan
Taipei, April 17 (CNA) Taipei Veterans General Hospital (TVGH) on Wednesday announced a research breakthrough that enables a simple blood test to detect individuals at high risk of Alzheimer's disease with around 90 percent accuracy by analyzing specific proteins in blood plasma.
Blood Test Predicts Dementia up to 10 Years in Advance, Study Finds
Blood biomarkers like tau217, NfL, and GFAP may predict dementia up to 10 years early, but aren’t yet reliable for widespread screening, a Karolinska Institutet study finds. A new study published in Nature Medicine has examined the potential of specific biomarkers, tau217, Neurofilament Light (NfL), and Glial Fibrillary Acidic Protein (GFAP), to predict the onset [...]
Medical Xpress
Science DailyHow do age, sex, hormones and genetics affect dementia biomarkers in the blood?
A new study has found important clues about the roles age, sex, hormonal changes and genetics play in how certain biomarkers for dementia are expressed in the blood. The study was published online in Neurology.
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