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Injectable ECM-Mimetic Dynamic Hydrogels Abolish Ferroptosis-Induced Post-Discectomy Herniation through Delivering Nucleus Pulposus Progenitor Cell-Derived Exosomes

Summary by Stemwell Science News
Investigators developed synthetically tailored nucleus pulposus progenitor cells-derived exosomes with enhanced miR-221-3p expression and nucleus pulposus cells uptake capacity, which were integrated into an injectable hydrogel based on ECM analogues. [Nature Communications] Full Article
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Injectable ECM-Mimetic Dynamic Hydrogels Abolish Ferroptosis-Induced Post-Discectomy Herniation through Delivering Nucleus Pulposus Progenitor Cell-Derived Exosomes

Investigators developed synthetically tailored nucleus pulposus progenitor cells-derived exosomes with enhanced miR-221-3p expression and nucleus pulposus cells uptake capacity, which were integrated into an injectable hydrogel based on ECM analogues. [Nature Communications] Full Article

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Stemwell Science News broke the news in on Thursday, April 3, 2025.
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