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'Master regulator' gene could lead to more effective treatment for patients with ovarian cancer

Summary by Medical Xpress
In a study co-led by the University of Maryland School of Medicine (UMSOM), researchers have identified a "master regulator" gene, ZNFX1, that may act as a biomarker to help guide treatment in future clinical trials involving patients with therapy-resistant ovarian cancer, according to a study recently published in Cancer Research.

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Medical XpressMedical Xpress
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'Master regulator' gene could lead to more effective treatment for patients with ovarian cancer

In a study co-led by the University of Maryland School of Medicine (UMSOM), researchers have identified a "master regulator" gene, ZNFX1, that may act as a biomarker to help guide treatment in future clinical trials involving patients with therapy-resistant ovarian cancer, according to a study recently published in Cancer Research.

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Stemwell Science NewsStemwell Science News

DDX54 Downregulation Enhances Anti-PD1 Therapy in Immune-Desert Lung Tumors with High Tumor Mutational Burden

Scientists identified DDX54 as a master regulator in immune-desert lung cancer with a high mutational burden, whose knockdown reduced resistance to immune checkpoint inhibitors. [Proceedings of The National Academy of Sciences of The United States of America] Abstract

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NewswiseNewswise

Researchers identify “master regulator” gene that could lead to more effective treatment for patients with ovarian cancer

In a study co-led by the University of Maryland School of Medicine (UMSOM), researchers have identified a "master regulator" gene, ZNFX1, that may act as a biomarker to help guide treatment in future clinical trials involving patients with therapy-resistant ovarian cancer, according to a study recently published in Cancer Research.

·Charlottesville, United States
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Medical Xpress broke the news in on Thursday, April 3, 2025.
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