Published 8 days ago

Recombinant Production and Functional Characterization of Andes Virus Gn and Gc in Pichia pastoris: A Path Towards Subunit Vaccine Development

Summary by preprints.org

Hantavirus Pulmonary Syndrome (HPS), caused by the Andes virus (ANDV), is a significant public health concern in South America, with no available vaccines or specific treatments. Neutralizing antibodies targeting ANDV glycoproteins Gn and Gc have shown protective effects in animal models, making them promising vaccine candidates. This study reports the recombinant expression, purification, and immunogenicity evaluation of sGn and sGc glycoprotei…

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Recombinant Production and Functional Characterization of Andes Virus Gn and Gc in Pichia pastoris: A Path Towards Subunit Vaccine Development

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